Multi-Omics atlas of the Brazilian COVID-19

About the project


COVID-19 is a respiratory syndrome which was declared world pandemic in March 2020. The worst pandemic in the last 100 years. The disease is caused by severe acute respiratory syndrome coronavirus 2, also known as SARS-CoV-2. Symptoms of COVID-19 are variable, but often include fever, cough, fatigue, breathing difficulties, and loss of smell and taste. While most people have mild symptoms, some people develop acute and severe reactions, which may lead to ICU admission and death. Until now, factors that lead to different symptoms are not totally known, possibly being a mixture of host and viral genetic factors.


This project aims to perform an extensive characterization of the microbial community in respiratory samples of patients with COVID-19. To achieve this goal, several omics approaches will be used, such as 16S/ITS microbial sequencing, shotgun metagenomics, RNA virome, and target SARS-CoV-2 sequencing.

By applying aforementioned approaches, we expect to generate data which will help the scientific community to understand how microbial composition and genetic factors may influence the outcomes of the disease. In total, 600 samples obtained by a partnership between Brazilian Health Ministry and Hospital ALbert Einstein will be included in this study.

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The people involved

Who are the people making the project happen.

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Partner organizations